实验室

时间：2025-12-15

「蛋白肌 Protein-Derm」高端功能性护肤体系

“蛋白肌”系列以重组蛋白材料科学为核心技术平台，将多肽工程、纳米递送与生物仿生学整合至日常护肤体系中，通过精准功效分层，实现从基础补水到深层再生的系统性肌肤修护。

在生命科学迅猛发展的时代，一场关于“皮肤未来”的革命正在悄然发生。传统护肤依赖提取、混合与堆叠，而我们相信，真正的焕肤力量，源自生命本身的语言——蛋白质。

蛋白肌（Protein Derma）诞生于蛋白质生物材料研究前沿。品牌创始团队来自国家重点实验室与医学转化中心，长期致力于胶原蛋白、弹性蛋白、类胶原蛋白（CLP）和类弹性蛋白（ELP）等新型生物材料的结构设计与功能开发。我们将这些成果，第一次带入美肤领域——让护肤从“成分堆叠”迈向“结构智造”。

在蛋白肌，我们不只是提取蛋白，我们在设计蛋白。
我们通过分子工程与绿色生物合成技术，重建蛋白质的序列、折叠与自组装，使其拥有更高的稳定性、生物亲和力与功效表现。每一款产品，都基于真实科研成果、临床转化思维以及严苛的生物材料标准进行打造。

于是，蛋白肌五大核心产品逐渐成形：

纳米胶原脂蛋白精萃水——修护从渗透开始高纯；

胶原蛋白乳——补充结构，重塑弹润；

ELP-CLP凝霜——重建屏障韧性高活性；

弹性蛋白面膜——深层紧致与弹性恢复线粒体

增强精华——点亮肌肤活力底座

它们不是简单的“护肤品”，而是源自蛋白工程技术的“功能性生物护肤系统”。从细胞外基质结构重建，到皮肤屏障修护，再到细胞能量提升——蛋白肌让“生物材料”真正服务于肌肤健康。

我们相信，未来的护肤不再是遮盖，而是利用生命本身的力量帮助肌肤自我更新。
我们相信，科技不应冰冷，而应温柔地被使用在每一寸皮肤之上。
我们更加相信，蛋白质将定义下一代美肤标准。

蛋白肌——让生物医学走向日常，让科学，让肌肤更好地“活着”。

蛋白肌·纳米胶原脂蛋白补水精华水

核心成分：纳米胶原脂蛋白 Nano-Collipo

功效亮点：深透补水 × 角质层修护 × 即刻弹润

本产品采用实验室自主开发的纳米胶原脂蛋白（Nano-Collipo）复合体 ——一种由重组胶原蛋白与类脂结构精确组装形成的双亲性纳米粒子。相比传统的水溶性胶原或原生胶原片段，Nano-Collipo 具有更高的皮肤兼容性、稳定性、生物黏附性和渗透能力，可高效通过角质层微结构进入浅层真皮。

纳米化后的蛋白结构依然保持天然胶原序列的活性，但具备更好的液体分散性与生物利用度，是当前蛋白工程材料在护肤领域的一项关键转化成果。

核心功效机制：不仅补水，而是重建皮肤微环境

（1）深透补水：以“水结构”稳定角质层

Nano-Collipo 中的纳米蛋白颗粒具有高亲水性和水分锁定能力，进入皮肤后可与天然NMF（Natural Moisturizing Factor）形成微弱相互作用，在角质层构建稳态含水结构，实现即刻且持续的补水效果。

（2）修护屏障：增强角质细胞间脂质排列

脂蛋白结构的引入，使得该精华水能模仿角质层脂质双层，促进脂质重排，有助于改善：

✓ 干燥敏感

✓ 屏障受损

✓ 洗后紧绷

这是传统玻尿酸水无法做到的屏障级修护。

（3）焕活肌底：为后续功效成分创造通路

纳米结构可轻度松动角质层紧密结构，使后续乳、霜、精华能够更高效吸收，从“补水”延伸到“导入”。

蛋白肌·胶原蛋白修护润肤乳

核心成分：高纯度重组胶原蛋白 rCLP

功效亮点：锁水保湿 × 提升紧致 × 改善肤感

采用高稳定性的重组类胶原蛋白，具备更强的成膜性与保湿力，可构筑“类真皮”保湿网络。质地轻盈不黏腻，连续使用可改善干燥粗糙与松弛，提升肌肤弹性。

核心功效机制：重建皮肤基底的“胶原生态”

（1）深层修护：与天然胶原协同构建微型ECM网络

ReCollagen 的活性序列可与皮肤成纤维细胞受体（如α2β1 integrin）结合，促进：

· 胶原合成

· 纤维排列重建

· 损伤组织愈合

实现真正意义上的“结构级修护”。

（2）增强屏障：乳液体系重整细胞间脂质结构

复合天然植物脂质及仿生磷脂，帮助：

· 恢复皮肤脂质层

· 减少TEWL（经表皮失水）

· 缓解干燥、粗糙与不耐受

在修护皮肤基底的同时，构建更加健康稳定的角质屏障。

（3）舒缓抗炎：降低刺激源对皮肤的反应性

ReCollagen 在微损伤与炎症皮肤中具有显著的免疫调节作用，可：

· 减少皮肤微炎症

· 提升耐受度

· 改善泛红不适

适合敏感肌、屏障受损肌长期使用。

产品优势：科研级胶原，功效型乳液的更高标准

① 人源重组胶原，安全性与活性远高于动物胶原

无免疫原性风险，更稳定、不易变性。

② “结构式修护”不是停留在表面，而是重建皮肤基底结构

帮助皮肤从“干燥敏感”向“健康稳定”转变。

③ 轻乳质地，高延展、高吸收

夏季可单独使用，冬季可叠加霜类，适应全年护理。

④ 与“蛋白肌”整个蛋白生态体系完美协同

前期用纳米胶原脂蛋白水深补水 →再用重组胶原乳进行结构修护 →后续再叠加霜与精华实现更深层调控。

蛋白肌·ELP-CLP 密集再生修护霜

核心成分：类弹性蛋白-类胶原复合物（ELP-CLP）

功效亮点：深层修护 × 强效抗皱 × 重塑弹性结构

ELP-CLP模拟人体真皮中的弹性蛋白与胶原协同结构，具有热响应凝胶与高韧性蛋白网络双重特性，可针对受损肌肤深层修护，显著改善表情纹、光老化皱纹，并提升紧致与轮廓支撑感，是系列中最具“修复力”的核心单品。

这款高阶修护霜以实验室原创的ELP-CLP 双蛋白体系 为核心：

· ELP（类弹性蛋白）：天然来源于 ECM 的弹性序列，具备独特 温敏可逆相转变，可在皮肤温度下形成柔性蛋白网络；

· CLP（类胶原蛋白）：高度仿生的三螺旋序列，可重建皮肤胶原结构、提升紧致度。

两者通过分子级“协同组装”，构成类似年轻真皮层的柔韧弹性网络，为面霜赋予 弹、润、紧、修 四大核心特性。

核心功效机制：构建皮肤专属的“弹性修护基底”

（1）重建弹性框架：ELP 的可逆网络赋予皮肤柔韧回弹力

ELP 在 32–34°C（皮肤表面温度）附近呈现 LCST 行为，形成柔性蛋白微凝聚网络，可：

· 提升皮肤弹性回弹

· 改善松弛与细纹

· 构建紧致而富有柔性的支撑结构

实现真正意义上的“结构性抗老”。

（2）深层修护：CLP 重塑胶原微环境

CLP 能与成纤维细胞受体特异结合，促进：

· 胶原再生

· ECM 排列重建

· 真皮层厚度与密度提升

从根源上增强皮肤韧性与健康度。

（3）屏障增强：蛋白基质结合仿生脂质层

通过蛋白–脂质协同结构，面霜可以：

· 深层锁水

· 强化屏障

· 明显降低干燥与敏感性反应

蛋白肌·弹性蛋白焕活精华

核心成分：重组弹性蛋白 rELP

功效亮点：提高弹性 × 改善松弛 × 促进自生胶原

运用工程化弹性蛋白，快速构建肌肤弹性网络，诱导成纤维细胞分泌天然胶原，改善松弛、毛孔粗大与肤质不均。适合需要提升饱满度与弹性的肌肤人群。

1. 科学底层逻辑：以多肽为“信号密码”重启肌肤再生程序

本款精华基于蛋白材料实验室的人源化多肽设计平台，精选短序列高活性信号肽群（Bioactive Peptide Cluster），通过精准的氨基酸序列调控实现对皮肤细胞的“信号重编程”。

核心理念：

用多肽语言与细胞对话，激活皮肤自愈与再生能力。

所使用的多肽包括：

· 胶原促进肽（Collagen-triggering peptides）：激活成纤维细胞胶原分泌

· 弹性恢复肽（Elasticity-regulating peptides）：促进弹性蛋白与纤维连接蛋白生成

· 修护信号肽（Regenerative micro-peptides）：调控炎症反应与细胞迁移

形成协同而强大的“高活性多肽群”。

2. 功效机制：三重结构与功能的深度修护

（1）重建 ECM：从源头提升胶原、弹性蛋白等基质蛋白合成

多肽直接作用于成纤维细胞受体，实现：

· 真皮层胶原密度↑

· 皮肤弹性↑

· 紧致度明显提升

属于真正的生物学级别抗老。

（2）调控微炎症：改善泛红、脆弱和疲劳状态

特定序列多肽能够抑制 TNF-α / IL-6 轻度慢性炎症，促进：

· 屏障修护

· 细胞迁移加速

· 皮肤愈合能力增强

特别适合敏感肌与易红肌人群。

（3）深吸收：纳米级分子精准递送

多肽分子量小、渗透性高，并通过纳米稳定化技术实现：

· 快速进入皮肤角质层下

· 高效靶向细胞作用

· 相较普通精华吸收更快、利用率更高

3. 产品优势：科研级信号调控科技带来的差异化体验

① 多肽群联合，而非单肽——功效更强、作用更全面

符合皮肤再生的真实生物信号模式。

② 高安全性与高生物相容性

多肽接近人体自有蛋白结构，几乎不致敏、不刺激。

③ 兼具抗老 + 修护 + 稳定肌肤三效合一

比传统抗老精华更“智能”，能主动调控皮肤状态。

④ 临床级效果构建，可搭配蛋白肌水乳霜形成完整体系

从“补水–修护–抗老”实现连续升级。

蛋白肌·弹性蛋白紧致修护面膜

核心成分：高分子弹性蛋白纤维膜材

功效亮点：一次性高浓度修复 × 强紧致 × 深入补水

运用弹性蛋白作为膜材基底，实现高含量蛋白的均匀释放。贴敷后形成“仿生ECM修护层”，迅速提升皮肤含水量、抚平细纹并强化屏障。特别适用于熬夜、晒后及医美术后的急救修护。

2. 技术优势：蛋白面膜远超传统“涂抹型修护”

（1）蛋白基“柔性支架”渗透——模拟真皮弹性网

重组弹性蛋白在皮肤温度下形成可逆自组装微凝胶，可：

· 渗透皮表皱褶

· 填充松弛结构

· 重建皮肤弹性框架

实现真正意义上的即时紧致 + 长效弹性提升。

（2）刺激弹性蛋白与胶原蛋白自然生物合成

激活成纤维细胞，促使皮肤自身生成 ECM：

· 提升皮肤密度

· 减少纹路产生

· 改善皮肤松弛与下垂

实现结构性抗老，不是表面“假紧致”。

（3）强修护：提升屏障耐受性、显著缓解干敏状态

蛋白层可迅速形成微型保护膜：

· 强力锁水

· 缓解泛红、紧绷、刺痛

· 提升抵御外界刺激的能力

适合敏感肌、医美修护期、干皮急救。

Protein-Derm® High-End Functional Skincare System

The Protein-Derm® product line is built on a core technology platform of recombinant protein materials science. It integrates peptide engineering, nano-delivery systems, and biomimetic science into daily skincare regimens. Through precision efficacy layering, it delivers systematic skin repair ranging from basic hydration to deep cellular regeneration.

In an era of rapid advancement in life sciences, a revolution in the "future of skincare" is quietly unfolding. Traditional skincare relies on extraction, mixing, and ingredient stacking, but we believe that the true power of skin rejuvenation stems from the language of life itself: proteins.

Protein-Derm® was born at the forefront of protein biomaterials research. Our founding team hails from national key laboratories and medical translation centers, with long-standing expertise in the structural design and functional development of advanced biomaterials such as collagen, elastin, collagen-like protein (CLP), and elastin-like protein (ELP). For the first time, we are bringing these scientific breakthroughs to the field of skincare—transforming the industry from "ingredient stacking" to "structural engineering".

At Protein-Derm®, we don’t just extract proteins—we design them.

Using molecular engineering and green biosynthesis technologies, we reconstruct protein sequences, folding patterns, and self-assembly properties to achieve superior stability, bioaffinity, and efficacy performance. Every product is developed based on authentic scientific research, clinical translation principles, and rigorous biomaterial standards.

Thus, the five core products of Protein-Derm® have taken shape:

1. Nano-Collipo Essence Toner – Repair begins with deep penetration

2. Recombinant Collagen Lotion – Replenishes structural support, restores firmness and hydration

3. ELP-CLP Regenerative Repair Cream – Rebuilds barrier resilience with high bioactivity

4. Elastin Firming Repair Mask – Delivers deep firming and elasticity restoration

5. Mitochondrial Boosting Serum – Ignites foundational skin vitality

These are not merely "skincare products"—they are functional bio-skincare systems derived from protein engineering technology. From extracellular matrix (ECM) structural reconstruction to skin barrier repair, and further to cellular energy enhancement—Protein-Derm® enables biomaterials to truly serve skin health.

We believe the future of skincare lies not in covering up imperfections, but in harnessing the power of life itself to facilitate skin self-renewal.

We believe technology should not be cold; it should be applied gently to every inch of skin.

Most importantly, we believe proteins will define the next generation of skincare standards.

Protein-Derm® – Bringing biomedical science to daily life. Let science help skin thrive.

Protein-Derm® Nano-Collipo Hydrating Essence Toner

Core Ingredient: Nano-Collipo (Nano-Collagen-Lipid Complex)Key Benefits: Deep Hydration × Stratum Corneum Repair × Instant Plumping

This product features the laboratory’s proprietary Nano-Collipo complex—a class of amphiphilic nanoparticles precisely assembled from recombinant collagen and lipid structures. Compared to conventional water-soluble collagen or native collagen fragments, Nano-Collipo exhibits superior skin compatibility, stability, bioadhesion, and penetration capacity, effectively passing through the stratum corneum microstructures to reach the superficial dermis.

The nano-engineered protein structure retains the bioactivity of natural collagen sequences while offering enhanced liquid dispersibility and bioavailability, representing a pivotal translational achievement of protein engineering materials in the skincare field.

Core Mechanism of Action: More than hydration—rebuilding the skin microenvironment

1. Deep Hydration: Stabilizes the stratum corneum with structured water retentionNano-Collipo particles possess high hydrophilicity and moisture-locking capabilities. Upon skin penetration, they form weak interactions with the skin’s natural NMF (Natural Moisturizing Factor), constructing a stable moisture-retaining structure in the stratum corneum for immediate and long-lasting hydration.

2. Barrier Repair: Enhances intercellular lipid arrangementThe incorporation of a lipoprotein structure allows the essence toner to mimic the stratum corneum lipid bilayer and promote lipid reorganization, helping to improve:✓ Dryness and sensitivity✓ Barrier damage✓ Post-cleansing tightnessThis level of barrier repair is unattainable with traditional hyaluronic acid toners.

3. Skin Priming: Creates pathways for subsequent active ingredientsThe nano-structure gently loosens the compact arrangement of the stratum corneum, enabling more efficient absorption of subsequent lotions, creams, and serums—extending the benefits from "hydration" to "enhanced penetration".

Protein-Derm® Recombinant Collagen Repair Lotion

Core Ingredient: High-Purity Recombinant Collagen-Like Protein (rCLP)Key Benefits: Long-Lasting Moisture Locking × Firmness Enhancement × Skin Texture Improvement

Formulated with highly stable recombinant collagen-like protein, it delivers superior film-forming properties and moisturizing efficacy to build a "dermis-like" moisturizing network. With a lightweight, non-greasy texture, consistent use improves dryness, roughness, and sagging, while enhancing skin elasticity.

Core Mechanism of Action: Rebuilding the "collagen ecosystem" of the skin matrix

1. Deep Repair: Synergistically constructs a micro-ECM network with native collagenThe bioactive sequences of ReCollagen bind to fibroblast receptors (e.g., α2β1 integrin), promoting:

• Collagen synthesis

• Fibrous tissue rearrangement

• Damaged tissue healingThis achieves true "structural-level repair".

2. Barrier Enhancement: The lotion system reorganizes intercellular lipid structureEnriched with natural plant lipids and biomimetic phospholipids, it helps to:

• Restore the skin lipid layer

• Reduce TEWL (Transepidermal Water Loss)

• Alleviate dryness, roughness, and skin intoleranceIt repairs the skin matrix while building a healthier, more stable stratum corneum barrier.

3. Soothing & Anti-Inflammatory: Reduces skin reactivity to irritantsReCollagen exerts significant immunomodulatory effects on micro-damaged and inflamed skin, capable of:

• Reducing skin micro-inflammation

• Enhancing skin tolerance

• Relieving redness and discomfortSuitable for long-term use by sensitive and barrier-damaged skin types.

Product Advantages: Scientific-grade collagen, setting a higher standard for functional lotions

1. Human-like recombinant collagen: Far superior to animal-derived collagen in safety and bioactivity, with no immunogenicity risk, enhanced stability, and resistance to denaturation.

2. "Structural repair": Targets the skin matrix rather than just the surface, transforming skin from "dry and sensitive" to "healthy and stable".

3. Lightweight lotion texture: Boasts high spreadability and absorbability—can be used alone in summer or layered under creams in winter, adapting to year-round skincare routines.

4. Perfect synergy with the full Protein-Derm® ecosystem:Nano-Collipo Essence Toner for deep hydration → Recombinant Collagen Lotion for structural repair → Follow-up creams and serums for deeper skin regulation.

Protein-Derm® ELP-CLP Intensive Regenerative Repair Cream

Core Ingredient: Elastin-like Protein-Collagen-like Protein Complex (ELP-CLP)Key Benefits: Deep Tissue Repair × Powerful Anti-Wrinkle × Elastic Structure Reconstruction

ELP-CLP mimics the synergistic structure of elastin and collagen in human dermis, featuring dual characteristics of thermoresponsive gelation and high-toughness protein network. It targets deep repair of damaged skin, significantly improves expression lines and photoaging wrinkles, and enhances skin firmness and contour definition. It is the most potent "repair-focused" core product in the line.

This advanced repair cream is centered on the laboratory’s original ELP-CLP dual-protein system:

• ELP (Elastin-like Protein): Derived from natural ECM elastic sequences, it exhibits unique thermally reversible phase transition properties, forming a flexible protein network at skin temperature.

• CLP (Collagen-like Protein): A highly biomimetic triple-helical sequence that rebuilds skin collagen structure and enhances firmness.

Through molecular-level "synergistic assembly", the two components form a flexible, elastic network similar to youthful dermal tissue, endowing the cream with four core properties: firmness, hydration, tightness, and repair.

Core Mechanism of Action: Building a skin-specific "elastic repair matrix"

1. Elastic Framework Reconstruction: ELP’s reversible network imparts flexible resilience to the skinELP exhibits LCST (Lower Critical Solution Temperature) behavior around 32–34°C (skin surface temperature), forming a flexible protein microcoacervate network that can:

• Enhance skin elasticity and bounce

• Improve sagging and fine lines

• Build a firm yet flexible supporting structureThis achieves true "structural anti-aging".

2. Deep Regeneration: CLP remodels the collagen microenvironmentCLP binds specifically to fibroblast receptors, promoting:

• Collagen regeneration

• ECM structural reorganization

• Improvement of dermal thickness and densityIt enhances skin toughness and health from the source.

3. Barrier Reinforcement: Protein matrix combined with biomimetic lipid layerThrough a protein-lipid synergistic structure, the cream can:

• Lock in moisture deeply

• Strengthen the skin barrier

• Significantly reduce dryness and sensitivity reactions

Protein-Derm® Elastin Revitalizing Serum

Core Ingredient: Recombinant Elastin-like Protein (rELP)Key Benefits: Elasticity Enhancement × Sagging Improvement × Endogenous Collagen Stimulation

Powered by engineered elastin, it rapidly builds a skin elasticity network, induces fibroblasts to secrete native collagen, and improves sagging, enlarged pores, and uneven skin texture. Suitable for individuals seeking enhanced skin plumpness and elasticity.

1. Scientific Rationale: Restarting skin regeneration with peptide "signal codes"

This serum is developed based on the protein materials laboratory’s humanized peptide design platform, featuring a selected cluster of short-sequence, high-bioactivity peptides. It achieves "signal reprogramming" of skin cells through precise amino acid sequence regulation.

Core Philosophy:Communicate with cells using the language of peptides to activate skin’s self-healing and regenerative capabilities.

The peptide complex includes:

• Collagen-triggering peptides: Stimulate collagen secretion in fibroblasts

• Elasticity-regulating peptides: Promote the production of elastin and fibronectin

• Regenerative micro-peptides: Regulate inflammatory responses and cell migration

Together, they form a synergistic and powerful bioactive peptide cluster.

2. Mechanism of Action: Three-dimensional structural and functional repair

1. ECM Reconstruction: Boosting synthesis of matrix proteins (collagen, elastin, etc.) at the sourcePeptides act directly on fibroblast receptors to achieve:

• ↑ Dermal collagen density

• ↑ Skin elasticity

• Significant improvement in firmnessThis represents true biological-level anti-aging.

2. Micro-Inflammation Regulation: Alleviating redness, fragility, and skin fatigueSpecific peptide sequences inhibit mild chronic inflammation mediated by TNF-α/IL-6, promoting:

• Barrier repair

• Accelerated cell migration

• Enhanced skin healing abilityParticularly suitable for sensitive and easily irritated skin types.

3. Deep Absorption: Targeted delivery via nanoscale moleculesWith small molecular weight and high permeability, combined with nano-stabilization technology, the serum achieves:

• Rapid penetration to the subcorneal layer

• Efficient targeted action on cells

• Faster absorption and higher utilization rate compared to conventional serums

3. Product Advantages: Differentiated experience with scientific-grade signal regulation technology

1. Peptide cluster synergy, not single peptides—delivering stronger, more comprehensive efficacy that aligns with the natural biological signaling patterns of skin regeneration.

2. High safety and bioaffinity—peptides closely resemble the body’s native protein structures, minimizing the risk of sensitization and irritation.

3. Triple-action formula: Anti-aging + Repair + Skin stabilization in one, making it a more "intelligent" alternative to traditional anti-aging serums with adaptive skin regulation capabilities.

4. Clinically validated efficacy: Designed to be used with the full Protein-Derm® toner-lotion-cream system, delivering a continuous upgrade from "hydration – repair – anti-aging".

Protein-Derm® Elastin Firming Repair Mask

Core Ingredient: High-Molecular-Weight Elastin Fiber MembraneKey Benefits: One-step high-concentration repair × Intensive firming × Deep hydration

Using elastin as the mask substrate, it enables uniform release of high-content proteins. Upon application, it forms a "biomimetic ECM repair layer", rapidly boosting skin moisture levels, smoothing fine lines, and strengthening the skin barrier. Ideal for emergency repair after staying up late, sun exposure, and cosmetic procedures.

2. Technological Advantages: Protein mask outperforms traditional "topical repair" products

1. Protein-based "flexible scaffold" penetration—mimicking the dermal elastic networkRecombinant elastin forms a reversible self-assembled microgel at skin temperature, which can:

• Penetrate skin surface wrinkles and fine lines

• Fill sagging structural gaps

• Rebuild skin’s elastic frameworkDelivering true instant firming + long-term elasticity enhancement.

2. Stimulating natural biosynthesis of elastin and collagenActivates fibroblasts to promote endogenous ECM production, resulting in:

• Improved skin density

• Reduction in wrinkle formation

• Improvement in skin sagging and ptosisAchieving structural anti-aging—not superficial "temporary firming".

3. Intensive Repair: Enhancing barrier tolerance and relieving dryness/sensitivityThe protein layer quickly forms a protective microfilm to:

• Lock in moisture effectively

• Alleviate redness, tightness, and stinging sensations

• Strengthen resistance to external irritantsSuitable for sensitive skin, post-procedure recovery, and dry skin emergency care.